CDT1 (D10F11) Rabbit mAb 8064S from Cell Signaling Technology

Product Specs
ItemCDT1 (D10F11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8064S
Quantity100 µl
ApplicationsW, IP, IF-IC
ReactivityH, Mk
TargetCDT1
HostRabbit
NCBI Gene AliasesDUP, RIS2
ClonalityMonoclonal
NCBI Full Gene Namechromatin licensing and DNA replication factor 1
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
CloneD10F11
Molecular Weight65

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) UBA3 reduction sensitizes cancer cells to NAE inhibitorsLife Sci AllianceApril 29, 2026Yu-Ling Miao, Li-Na Zhou, Shan-Shan Song, Xu-Bin Bao, Xia-Juan Huan, Jian Ding, Jin-Xue HeSigma-Aldrich), aliquoted, and stored at −20°C. Antibodies against NAE1/APPBP1 (#14321S), Ubc12 (#5641S), Cdt1 (#8064S), p27 (#3688S), pIκBα (ser32/36; #9246S), and LC3A/B (#4108s) were purchased from Cell Signaling Technology.

(2) Multi-omic analysis of human PHACTR1 signaling networksCommunications BiologyJanuary 19, 2026Kathryn Wolhuter, Lijiang Ma, Nicole S. Bryce, Osvaldo Contreras, Natalie Mellett, Ling Zhong, Chris Thekkedam, Siiri E. Iismaa, Corey Giles, Richard P. Harvey, et al.#ab110412), HMOX1 (Santa Cruz Biotechnology, #sc-7695) and the following all from Cell Signaling: CDT1 (#8064), Thymidine Kinase 1 (#28755), Phospho-Histone H3 (Ser10, #53348), Cyclin A2 (#91500), Cyclin B1 (#12231),

(3) DNA damage checkpoints balance a tradeoff between diploid- and polyploid-derived arrest failuresCell ReportsOctober 28, 2025Kotaro Fujimaki, Ashwini Jambhekar, Galit Lahavanti-H2A.X-P(Ser139),Millipore,JBW301; RRID: AB_310795 Rabbit monoclonal anti-CDT1,Cell Signaling Technology,D10F11; Cat# 8064; RRID: AB_10896851 Mouse monoclonal anti-GMNN,DSHB,Cat# CPTC-GMNN-1; RRID: AB_2617263 Mouse monoclonal

(4) A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damagebioRxivSeptember 11, 2025Thomas Moss, Alexandra Wooldredge, Koustav Bhakta, Matthew Cronin, Jason E. Gestwicki, Shaeri Mukherjee(53348S) Cyclin E,1:1000,Santa Cruz Biotechnology (sc-247) CDT1,1:1000,Cell Signaling Technology (8064S) Lamin B1,1:1000,Proteintech (12987-1-AP) Cyclin A,1:1000,Santa Cruz Biotechnology (sc-271682) Polβ,1:1000,Proteintech

(5) Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma CellsCancer Res CommunJune 6, 2025Stacia L. Koppenhafer, Elizabeth L. Geary, Mary V. Thomas, Emma E. Croushore, Jessica A.O. Zimmerman, Jenna M. Gedminas, Dawn E. Quelle, Rebecca D. Dodd, David J. GordonRRID:AB_2141973), MCM5 (Proteintech, #11703-1-AP, 1:1,000, RRID:AB_2235162), CDT1 (Cell Signaling Technology, #8064, 1:1,000, RRID:AB_10896851), RRM1 (Cell Signaling Technology, #8637, 1:1,000, RRID:AB_10896851), RRM2

(6) The class II myosin MYH4 safeguards genome integrity and suppresses tumor progressionJ Clin InvestJune 2, 2025Jayashree Thatte, Ana Moisés da Silva, Judit Börcsök, Thorkell Gudjónsson, Jan Benada, Xin Li, Muthiah Bose, Hanneke van der Gulden, Ji-Ying Song, Renée Menezes, et al.rabbit anti-CDC6 (Cell Signaling Technology, 3387S), and rabbit anti-CDT1 (Cell Signaling Technology, 8064S). Synergy analysis A dose-response matrix experiment was conducted using 5 different concentrations

(7) Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumorbioRxivDecember 17, 2024Patricia D.B. Tiburcio, Kenian Chen, Lin Xu, Kenneth S. Chen1:1,000), Cyclin D2 (Cell Signaling Technology 3741; RRID:AB_2070685), CDT1 (Cell Signaling Technology 8064, RRID:AB_10896851), Cyclin E1 Cell Signaling Technology 20808, RRID:AB_2783554), Cyclin A2 (Cell Signaling

(8) Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infectionPLOS PathogensDecember 5, 2024Jason M. Needham, Sarah E. Perritt, Sunnie R. ThompsonRRID:AB_1640207, Cdc6: Cell Signaling Technologies 3387T RRID:AB_2078525, Cdt1: Cell Signaling Technologies 8064S RRID:AB_10896851, Geminin: Abcam ab195047 RRID:AB_2832993, Tubulin: Cell Signaling 2146 RRID:AB_2210545,

(9) RepID as a potential biomarker and therapeutic target for lung neuroendocrine tumorScientific ReportsNovember 11, 2024Jong-Uk Park, Jae-Hyun Jo, Sangjune Kim, Christophe E. Redon, Mirit I. Aladjem, Yuri Seo, Se Jin Jang, Sang-Min Janganti-CUL4B (Sigma, C9995, 1:2000), anti-RepID (Abcam, ab86244, 1:2000), anti-CDT1 (Cell Signaling, 8064, 1:2000), anti-FLAG (Sigma, F1804, 1:1000), anti-a-tubulin (Sigma, T9026, 1:10,000), and anti-histone H3

(10) Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical developmentFrontiers in Molecular NeuroscienceNovember 6, 2024Emma LaNoce, Daniel Y. Zhang, Alan Garcia-Epelboim, Yijing Su, Yusha Sun, Giana Alepa, Angelina R. Angelucci, Cagla Akay-Espinoza, Kelly L. Jordan-Sciutto, Hongjun Song, et al.regulation (P21, CDT1), which were incubated at the following concentrations: CDT1 (Cell Signaling, 8064; 1:200), Laminin (Sigma-Aldrich, L9393; 1:500), Nestin (Abcam, ab105389; 1:300 and Santa Cruz, sc-21247;

(11) CDK-independent role of D-type cyclins in regulating DNA mismatch repairMolecular CellApril 4, 2024Gergely Rona, Bearach Miwatani-Minter, Qingyue Zhang, Hailey V. Goldberg, Marc A. Kerzhnerman, Jesse B. Howard, Daniele Simoneschi, Ethan Lane, John W. Hobbs, Elizabeth Sassani, et al.(1:1000),Cell Signaling Technology,"Cat#3136, RRID: AB_2229289" CDT1 (1:1000),Cell Signaling Technology,"Cat#8064S, RRID: AB_10896851" CDT2 (1:1000),Bethyl Laboratories,"Cat#A300-948A, RRID: AB_2093890" CHK2 (1:1000),Cell Signaling Technology

(12) DCAF14 regulates CDT2 to promote SET8-dependent replication fork protectionLife science allianceJanuary 1, 2024Tirado-Class N, Hathaway C, Nelligan A, Nguyen T, Dungrawala H.described: DCAF14 (1:500, WB, NBP2-33883; Novus), CDT2 (1:500, WB, ABS500; Millipore), CDT1 (1:500, WB, 8064S; CST), SET8 (1:500, WB, 06-1304; Millipore and 1:200, IF, 2996T; CST), P21 (1:500, WB and 1:200, IF,

(13) APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrestbioRxivNovember 14, 2023Brandon L Mouery, Eliyambuya M Baker, Christine A Mills, Laura E Herring, Dalia Fleifel, Jeanette Gowen CookBethyl Laboratories; milk), Geminin (1:3000; rabbit; sc-13015; Santa Cruz Biotechnology; milk), Cdt1 (1:1000, rabbit, 8064, Cell Signaling Technology, milk), donkey-anti-mouse-HRP (1:10,000; 715-035-150; Jackson ImmunoResearch),

(14) Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replicationMolecular Cancer TherapeuticsAugust 1, 2023Junko Murai, Michele Ceribelli, Haiqing Fu, Christophe E. Redon, Ukhyun Jo, Yasuhisa Murai, Mirit I. Aladjem, Craig J. Thomas, Yves PommierCell Signaling), the anti-BrdU (B44) (347580, mouse monoclonal, Becton Dickinson) and the anti-CDT1 (D10F11) (8064, rabbit monoclonal, Cell Signaling) were used. Quantitative high-throughput screen Each of the 1,948

(15) Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutationsThe Journal of clinical investigationJuly 3, 2023Zhao Z, Cao K, Watanabe J, Philips CN, Zeidner JM, Ishi Y, Wang Q, Gold SR, Junkins K, Bartom ET, et al.33510), anti-PTIP (Bethyl Laboratories, A300-370A), ASH2L (CST, 5019), H3 Ser10-p (CST 53348), CDT1 (CST, 8064), Cyclin B1 (CST, 12231), Geminin (CST, 52508), Cyclin E1 (CST, 20808), Cyclin A2 (CST, 91500), p-cdc2

(16) Compartmentalisation of Hepatitis B virus X gene evolution in hepatocellular carcinoma microenvironment and the genotype-phenotype correlation of tumorigenicity in HBV-related patients with hepatocellular carcinomaEmerging Microbes & InfectionsDecember 31, 2022Ya Fu, Fengling Fang, Hongyan Guo, Xialin Xiao, Yuhai Hu, Yongbin Zeng, Tianbin Chen, Songhang Wu, Ni Lin, Jinlan Huang, et al.(#9309, CST, USA), pRb (##8516, CST, USA), E2F1 (ab288369, Abcam, UK), ATM (#2873, CST, USA), CDT1 (#8064, CST, USA), MYC (#5605, CST, USA), TOP1 (ab109374, Abcam, UK) and β-actin (#4970, CST, USA). Analysis

(17) SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapyNeoplasia (New York, N.Y.)October 1, 2022Zhou LN, Xiong C, Cheng YJ, Song SS, Bao XB, Huan XJ, Wang TY, Zhang A, Miao ZH, He JX.(#5641S); UBE2C (#14234S); Ubc9 (#4786S); Cul3 (#2759S); Cul4A (#2699S); NAE1/APPBP1 (#14321S); Cdt1 (#8064S); p27 (#3688S); p-Chk1-Ser317 (#2344S); Chk1 (#2360S); p-Chk2-T68 (#2661S); γH2AX (#2577L); Caspase-8

(18) Transcriptome Analysis of the Anti-Proliferative Effects of Ginsenoside Rh3 on HCT116 Colorectal Cancer CellsMoleculesAugust 6, 2022Siying Teng, Xi Lei, Xinmin Zhang, Dongming Shen, Qiuyi Liu, Yingjie Sun, Yi Wang, Zhongyi CongTechnology (CST) or Beyotime: Mcm2 (3619T, 1:2000, CST), phosphorylated Mcm2 (8861S, 1:3000, CST), Cdt1 (8064S, 1:3000, CST), Orc6 (4737S, 1:2000, CST), β-Catenin (8480S, 1:2000, CST), MMP-9 (13667S, 1:1000, CST),

(19) Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancerScience advancesMay 13, 2022Stanzione M, Zhong J, Wong E, LaSalle TJ, Wise JF, Simoneau A, Myers DT, Phat S, Sade-Feldman M, Lawrence MS, et al.Cell Signaling Technology; or pH 6.0; 1:200; ab26350, Abcam), Ki67 (pH 6.0; 1:150; ab15580, Abcam), CDT1 (pH 9.0; 1:150; 8064, Cell Signaling Technology), GEMININ (pH 9.0; 1:100; Geminin-L-CE, Leica Microsystems; or pH 6.0; 1:350;

(20) Genetic instability from a single S phase after whole-genome duplicationNatureApril 1, 2022Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé AS, Tijhuis AE, Bernhard SV, Spierings DCJ, Simon A, et al.mouse anti-CDC6 (1:500; Santa Cruz sc-9964, RRID AB 627236), rabbit anti-CDT1 (1:500; Cell Signaling 8064S, RRID AB 10896851), rabbit anti-treslin (1:500; Betyl A303-472A, RRID AB 10953949), goat anti-rabbit

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CDT1 (D10F11) Rabbit mAb

CDT1 (D10F11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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CDT1 (D10F11) Rabbit mAb from Cell Signaling Technology

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