Cleaved Caspase-9 (Asp330) (D2D4) Rabbit mAb from Cell Signaling Technology

Yes, the Cleaved Caspase-9 (Asp330) (D2D4) Rabbit mAb has been utilized in various studies to investigate apoptosis in cancer cells. For instance, in the study by Chen et al. (2016), the antibody was used to measure the expression of cleaved caspase-9 in triple-negative breast cancer cells treated with chemotherapeutic agents, demonstrating its role in apoptosis regulation.

The Cleaved Caspase-9 antibody has been shown to work effectively in Western blot applications, as evidenced by its use in multiple studies, including those by Dey et al. (2018) and Gong et al. (2018), where it was employed to detect cleaved caspase-9 in various cancer cell lines.

The antibody has been used to detect increased levels of cleaved caspase-9 in response to treatments that induce apoptosis, such as glutamine deprivation and the use of chemotherapeutic agents like etoposide and cisplatin, as reported in the study by Chen et al. (2016).

The Cleaved Caspase-9 (Asp330) antibody is specifically reactive to human caspase-9, which may limit its application in studies involving non-human species. It is important to consider this specificity when designing experiments that involve animal models or other species.