MyBioSource.com's Mouse Anti Human Interleukin-8 is a Mouse monoclonal antibody. The Mouse Anti Human Interleukin-8 Antibody was generated using CXCL8, and GCP1 as the antigen. It reacts with Non-Human Primate. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Introduction: Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies.When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytosethe particle. Upon processing, they release chemokinesto signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophilsat the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor