Myosin IIc (D4A7) Rabbit mAb 8189S from Cell Signaling Technology

Product Specs
ItemMyosin IIc (D4A7) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8189S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH, M, R, Mk
TargetMyosin IIc
HostRabbit
NCBI Gene AliasesDFNA4, DFNA4A, FP17425, MHC16, MYH17, NMHC II-C, NMHC-II-C, PNMHH, myosin
ClonalityMonoclonal
NCBI Full Gene Namemyosin heavy chain 14
Research AreaCytoskeletal Signaling
IsotypeIgG
CloneD4A7
Molecular Weight230

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Myosin IIA motor regulates attaching-effacing bacteria interactions with intestinal epitheliumGut MicrobesDecember 31, 2026Nayden G. Naydenov, Atif Zafar, Susana Lechuga, Ajay Zalavadia, Armando Marino-Melendez, John A. Hammer, Velia M. Fowler, Christine McDonald, Kenneth G. Campellone, Andrei I. Ivanov#909801), LPS mAb (Abcam, Waltham, MA cat. #35654), NM IIC (D4A7) mAb (Cell Signaling, Beverly, MA cat. #8189S), and GAPDH (14C10) mAb (Cell Signaling, cat. #2118). Alexa Fluor-488- or Alexa Fluor-568-conjugated

(2) Regulation of the formin INF2 by actin monomers and calcium/calmodulinJournal of Cell BiologyFebruary 2, 2026Miriam Lee, Aiman Jalmukhambetova, T. Emme Burgin, Henry N. HiggsAnti-Myosin IIA (rabbit, 3403; Cell Signaling Technology) was used at 1:1,000. Anti-Myosin IIC (rabbit, 8189; Cell Signaling Technology) was used at 1:1,000. Anti-fascin (mouse, SC-21743; Santa Cruz Biotechnology)

(3) Non-muscle myosin IIC predominantly expressed in the slow-twitch skeletal muscles impedes age-related muscle weaknessPLoS OneDecember 4, 2025Hiroki Hamaguchi, Shino Hiraoka, Kun Tang, Haonan Zhu, Yoshitaka Mita, Yasuro Furuichi, Nobuharu L. Fujii, Yasuko Manabemin at room temperature and incubated with the primary antibodies against NMIIC (rabbit, monoclonal, 8189; Cell Signaling, MA, USA) and laminin-α2 (rabbit, polyclonal, L9393; Sigma-Aldrich) overnight at 4 °C.

(4) Salidroside inhibits melanin synthesis and melanoma growth via mTOR and PI3K/Akt pathwaysFront OncolJuly 10, 2025Qi Ouyang, Shengye Tian, Hengyu Zhou, Ying Mao, Xiang Li, Feng Yan, Ailong Liu, Xiang Hu, Changqiao You, Jun HeNrf2 (1:200, Cell Signaling Technology, 12721S) and the slides incubated with Ki-67 (Immunoway, YM 8189) and mTOR (1:200, Zenbio, R380411) Thereafter, the cells were incubated with fluorescence-conjugated

(5) Genome-wide CRISPR Screening Identifies NFκB and c-MET as Druggable Targets to Sensitize Lenvatinib Treatment in Hepatocellular CarcinomaCellular and Molecular Gastroenterology and HepatologyMarch 20, 2025Ting-Chi Rebecca Wan, W E I Wei, Lai-Hung Cheng, Wai-Ching Chin, Jialing Shen, For-Fan Chan, Zhijian Kuang, Cun Wang, Carmen Chak-Lui Wong, Chun-Ming Wonganti-NFKB1 (1:1000, Cell Signaling Technology #13586), anti-MET antibody (1:1000, Cell Signaling Technology #8189), and anti-α/β-Tubulin Antibody (1:1000, Cell Signaling Technology #2148). Proliferation Assay Cells

(6) Patterning and folding of intestinal villi by active mesenchymal dewettingCellJune 6, 2024Huycke TR, Häkkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, et al.RRID:AB_2734686 Rabbit anti-MYH10,BioLegend,Cat#909901; RRID:AB_2749903 Rabbit anti-MYH14,Cell Signaling Technology,Cat#8189S; RRID:AB_2565101 Rabit anti-pMLC,abcam,Cat#ab2480; RRID:AB_303094 Mouse anti-MYLK,Sigma,Cat#SAB4200808;

(7) Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movementPLoS geneticsJune 1, 2024Du W, Verma A, Ye Q, Du W, Lin S, Yamanaka A, Klein OD, Hu JK.RRID:AB_944320), myosin IIB (1:100, Biolegend, 909901, RRID:AB_2565101), myosin IIC (1:100, Cell Signaling, 8189S, RRID:AB_10886923), pAKT (1:100, Cell Signaling, 9271, RRID:AB_329825), pMLC (1:100, Abcam, ab2480,

(8) Patterning and folding of intestinal villi by active mesenchymal dewettingbioRxiv : the preprint server for biologyAugust 15, 2023Huycke TR, Miyazaki H, Häkkinen TJ, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, et al.(1:100),BioLegend,#909901 MYH10 (1:100),BioLegend,#909802 MYH14 (1:100),Cell Signaling Technology,#8189s pMLC (1:100),abcam,#ab2480 MYLK (1:50),Sigma,#SAB4200808 Fibronectin (1:300),Abcam,#ab2413 Collagen

(9) Cell contractility drives mechanical memory of oral squamous cell carcinomaMolecular Biology of the CellAugust 1, 2023So Youn Moon, Paloma Santos de Campos, Bibiana Franzen Matte, Jesse K. Placone, Virgı´lio G. Zanella, Manoela D. Martins, Marcelo Lazzaron Lamers, Adam J. Engler(1:500, Cell Signaling, #3403), NMM2B (1:500, Cell Signaling, #8824), NMM2C (1:500, Cell Signaling, #8189), E-cadherin (1:1000, Cell Signaling, #3915), N-cadherin (1:1000, Cell Signaling, #13116), pFAK (1:1000,

(10) Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membraneThe Journal of cell biologyJuly 3, 2023Rouaud F, Huang W, Flinois A, Jain K, Vasileva E, Di Mattia T, Mauperin M, Parry DAD, Dugina V, Chaponnier C, et al.specificity of antibodies against NM2A (n. 909801; BioLegend), NM2B (n. 909901; BioLegend), and NM2C (n. 8189; Cell Signaling Technology) was verified in previous studies (Nguyen-Ngoc et al., 2017; Heuzé et al.,

(11) Myosin II proteins are required for organization of calcium-induced actin networks upstream of mitochondrial divisionMolecular biology of the cellJune 1, 2022Kage F, Vicente-Manzanares M, McEwan BC, Kettenbach AN, Higgs HN.Cell Signaling Technology; 1:1000). NMIIB (rabbit; 3404; Cell Signaling Technology; 1:1000). NMIIC (rabbit; 8189; Cell Signaling Technology; 1:1000). MRLC (rabbit; 3672; Cell Signaling Technology; 1:1000). Phospho

(12) Deficiency of Klc2 Induces Low-Frequency Sensorineural Hearing Loss in C57BL/6 J Mice and HumanMolecular neurobiologySeptember 1, 2021Fu X, An Y, Wang H, Li P, Lin J, Yuan J, Yue R, Jin Y, Gao J, Chai R.blot kit. The following antibodies were used: anti-Klc2 (Proteintech, 17668-1-AP), anti-Myh14 (CST, 8189P), anti-Gapdh (Boster, BM1623). RNA extraction and quantitative real time-polymerase chain reaction

(13) Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphodynamicseLifeAugust 10, 2021Weißenbruch K, Grewe J, Hippler M, Fladung M, Tremmel M, Stricker K, Schwarz US, Bastmeyer M.#909801), rabbit polyclonal to NMHC IIB (BioLegend, #909901), rabbit monoclonal to NMHC IIC (CST, #8189S), rabbit polyclonal to GFP (Abcam, #ab6556). Secondary horseradish peroxidase-coupled anti-mouse or

(14) Myosin IIA drives membrane bleb retractionMolecular biology of the cellApril 15, 2019Taneja N, Burnette DT.(#909801) was purchased from BioLegends (San Diego, CA). Rabbit anti-myosin IIB (#8824S) and myosin IIC (#8189) were purchased from Cell Signaling Technology (Danvers, MA). Mouse anti-tubulin (#T6199) was purchased

(15) BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeabilityMucosal immunologySeptember 1, 2018Choksi YA, Reddy VK, Singh K, Barrett CW, Short SP, Parang B, Keating CE, Thompson JJ, Verriere TG, Brown RE, et al.#8505S), anti-phospho-myosin light chain 2(Cell Signaling, #3674S), or Myosin 2C (Cell Signaling, #8189S). All antibodies were used at 1:1000 concentration (except anti-β-actin, 1:2000) in Odyssey blocking

(16) Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulationScientific reportsFebruary 27, 2018Singh AP, Sharma S, Pagarware K, Siraji RA, Ansari I, Mandal A, Walling P, Aijaz S.Cell Signaling Technology), Myosin IIB (#3404, rabbit polyclonal, Cell Signaling Technology), Myosin IIC (#8189, rabbit monoclonal, Cell Signaling Technology), GFP (#2955, mouse monoclonal, Cell Signaling Technology),

(17) Myosin IIa is critical for cAMP-mediated endothelial secretion of von Willebrand factorBloodFebruary 8, 2018Li P, Wei G, Cao Y, Deng Q, Han X, Huang X, Huo Y, He Y, Chen L, Luo J.polyclonal antibody to myosin IIc (Biolegend, PRB-444P), rabbit monoclonal antibody to myosin IIc (CST, 8189), and HRPconjugated secondary antibodies (anti-rabbit NA9340 and anti- MYOSIN IIa REGULATES ENDOTHELIAL

(18) Exposure to phthalate esters induces an autophagic response in male germ cellsEnvironmental EpigeneticsAugust 3, 2017Paula Valenzuela-Leon, Ina Dobrinski

(19) X-radiation enhances the collagen type I strap formation and migration potentials of colon cancer cellsOncotargetNovember 1, 2016Stephanie Blockhuys, Na Liu, Nisha Rani Agarwal, Annika Enejder, Vesa Loitto, Xiao-Feng Sunanti-integrin β1 (#4706), anti-MLC2 (#3672), anti-NMHCIIA (#3403), anti-NMHCIIB (#3404), anti-NMHCIIC (#8189), Alexa Fluor® 488-conjugated anti-mouse IgG (H+L) antibodies from Cell Signaling Technologies (Danvers,

(20) Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancerAmerican journal of physiology. Gastrointestinal and liver physiologyJune 1, 2016Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D.Experiments Antibodies. Two different antibodies against FOXA2 were used. One was used for Western blotting experiments (8189; Cell Signaling) and the other (sc-6554; Santa Cruz Biotechnology) for IHC analysis. PLAUR antibody

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Myosin IIc (D4A7) Rabbit mAb

Myosin IIc (D4A7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Myosin IIc (D4A7) Rabbit mAb from Cell Signaling Technology

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