MyBioSource.com's RAT ANTI HUMAN EGF RECEPTOR is a Rat monoclonal antibody. The RAT ANTI HUMAN EGF RECEPTOR Antibody was generated using EGFR, egfra, epidermal growth factor receptor, ERBB, ERBB1, Errp, and HER1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, and Immunoprecipitation.
Description
Rat anti Human EGF Receptor antibody, clone ICR10 recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Rat anti Human EGF Receptor antibody, clone ICR10 binds to epitope B from EGFR (Lottaz et al. 2010 and Modjtahedi et al. 1993) and has an affinity of 6.7 x 10-9 M