Aviva Systems Biology's TNFRSF10A Antibody (OAEE00165) is a Mouse monoclonal antibody. The TNFRSF10A Antibody (OAEE00165) was generated using TNFRSF10A as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Cell Sorting, Isolation, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B