PE/Cyanine5 anti-human CD4 317412 from BioLegend

Product Specs
ItemPE/Cyanine5 anti-human CD4
CompanyBioLegend
Price $276.00Supplier Page View Company Product Page
Catalog Number317412
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
Conjugate/TagPE/Cyanine5
IsotypeMouse IgG2b, kappa
Quantity100 tests
ApplicationsFC - Quality tested
CloneOKT4
ReactivityHuman, Cynomolgus, Rhesus
HostMouse
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ClonalityMonoclonal
ImmunogenHuman peripheral T cells
TargetCD4
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Heterologous betacoronavirus spike immunization in nonhuman primates elicits cross-reactive antibodies that neutralize both sarbeco- and merbecovirusesbioRxivFebruary 6, 2026Katharina Dueker, Tazio Capozzola, Ziqi Feng, Ryan N. Lin, Jonathan Hurtado, Sandhya Bangaru, Meng Yuan, Nathan Beutler, Elijah Garcia, Wan-ting He, et al.#557760), CD14 (M5E2, BD Pharmingen #561384), IgM (MHM-88, Biolegend #314508), CD4 (OKT-4, Biolegend #317411), CXCR5 (Mu5UBEE, ThermoFisher #25–9185-41), CD38 (AT-1, Stem Cell Technologies #60131FI), CD20 (2H7,

(2) Systems immunology analysis of human immune organoids identifies host-specific correlates of protection to different influenza vaccinesCell Stem CellApril 3, 2025Zachary W. Wagoner, Timothy B. Yates, Jenny E. Hernandez-Davies, Suhas Sureshchandra, Erika M. Joloya, Aarti Jain, Rafael de Assis, Jenna M. Kastenschmidt, Andrew M. Sorn, Mahina Tabassum Mitul, et al.CD39 (A1) BV785,Biolegend,Cat # 328240; RRID: AB_2814191 Anti-Human CD4 (OKT4) PE/Cy5,Biolegend,Cat # 317412; RRID; AB_571957 Anti-Human CD4 (OKT4) PE/Cy7,Biolegend,Cat # 317414; RRID: AB_571959 Anti-Human CD45

(3) Bile acid metabolites predict multiple sclerosis progression and supplementation is safe in progressive diseaseMedMarch 14, 2025Dimitrios C. Ladakis, Kimystian L. Harrison, Matthew D. Smith, Krista Solem, Sachin Gadani, Larissa Jank, Soonmyung Hwang, Farzaneh Farhadi, Blake E. Dewey, Kathryn C. Fitzgerald, et al.2564085 CD3_BV786 Clone:SK7 Dil:80,BD,Cat#563800; RRID: AB 2744384 CD4_PE-Cy5 Clone:OKT4 Dil:80,Biolegend,Cat#317412; RRID: AB 571957 CD8_BV480 Clone:RPA-T8 Dil:80,BD,Cat#566121; RRID: AB 2739523 CD45RA_BV570 Clone:HI100

(4) Expanded CD8 + CD38 + T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective StudyACR Open RheumatologyDecember 1, 2024Jose Rubio, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O'Connell, George C. Tsokos, Vasileios Kyttarisstained as previously described 11 with CD3‐APC (BioLegend, Cat# 300439), CD4‐PeCy5 (BioLegend, Cat# 317412), CD8‐PE (BioLegend, Cat# 344706), and CD38‐PeCy7 (BioLegend, Cat# 303516) markers and later analyzed

(5) Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruptionNature immunologyOctober 1, 2024Pereira Ribeiro S, Strongin Z, Soudeyns H, Ten-Caten F, Ghneim K, Pacheco Sanchez G, Xavier de Medeiros G, Del Rio Estrada PM, Pelletier AN, Hoang T, et al.no. 612815), anti-CD3 (clone SP34-2; BD cat. no. 564117), anti-CD4 (clone OKT4; BioLegend cat. no. 317412), anti-CD8 (clone RPA-T8; BD cat. no. 612942) and anti-CD95 (clone DX2; BioLegend cat. no. 305628).

(6) Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistenceNature ImmunologyJuly 1, 2024Zachary Strongin, Laurence Raymond Raymond Marchand, Claire Deleage, M. Betina Pampena, Maria Andrea Cardenas, Christian Michel Beusch, Timothy N. Hoang, Elizabeth A. Urban, Mael Gourves, Kevin Nguyen, et al.328228), anti-PD-1-BV785 (clone EH12.2H7, catalog no. 329930), anti-CD4-PE/Cy5 (clone OKT4, catalog no. 317412), anti-CD101-PE/Cy7 (clone BB27, catalog no. 331014) (all from Biolegend); anti-CTLA-4-BV421 (clone

(7) Detection of the interactions of tumour derived extracellular vesicles with immune cells is dependent on EV-labelling methodsJournal of extracellular vesiclesDecember 1, 2023Loconte L, Arguedas D, El R, Zhou A, Chipont A, Guyonnet L, Guerin C, Piovesana E, Vázquez-Ibar JL, Joliot A, et al.anti‐CD3 Alexa‐Fluor 647 (BD Pharmigen #300416, clone UCHT1, diluted 1/100), anti‐CD4 PE/Cy5 (Biolegend #317412, clone OKT4, diluted 1/100), anti‐CD8 PE (Biolegend # 34706, clone SK1, diluted 1/100), anti‐CD11c BUV395

(8) Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoidsImmunityAugust 8, 2023Kastenschmidt JM, Sureshchandra S, Jain A, Hernandez-Davies JE, de Assis R, Wagoner ZW, Sorn AM, Mitul MT, Benchorin AI, Levendosky E, et al.CD4 (OKT4) FITC,Biolegend,cat # 317408; RRID: AB_571951 Anti-Human CD4 (OKT4) PE-Cy5,Biolegend,cat # 317412; RRID; AB_571957 Anti-Human CD45 (HI30) AF700,Biolegend,cat # 304024; RRID: AB_493761 Anti-Human CD45RA

(9) T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockadeJCI insightJune 22, 2023Lee K, Thompson EA, Gharaie S, Patel CH, Kurzhagen JT, Pierorazio PM, Arend LJ, Thomas AG, Noel S, Slusher BS, et al.563352), BV711 anti-PD1 (clone EH12.2H7, BioLegend, 329928), PE-Cy5 anti-CD4 (clone OKT4, BioLegend, 317412), PE-Cy5.5 anti-CD69 (clone CH/4, Thermo Fisher Scientific, MHCD6918), APC anti-CD49a (clone TS2/7,

(10) Stripenn detects architectural stripes from chromatin conformation data using computer visionNature communicationsMarch 24, 2022Yoon S, Chandra A, Vahedi G.CD19 (BioLegend, cat#302205), anti-human CD8 (BioLegend, cat#301040), anti-human CD4 (BioLegend, cat#317411). Computational analysis Stripenn Stripenn detects architectural stripes from chromatin conformation

(11) Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccinationiScienceSeptember 24, 2021Carre C, Wong G, Narang V, Tan C, Chong J, Chin HX, Xu W, Lu Y, Chua M, Poidinger M, et al.AF700, HCD14",Biolegend,325614 "CD3, BV605, OKT3",Biolegend,317322 "CD4, PE/Cy5, OKT4",Biolegend,317412 "IgG surface, FITC, G18-145",BD,555786 "IgM surface, APC/Cy7, MHM-88",Biolegend,314520 "IgG intra,

(12) HTNV infection of CD8(+) T cells is associated with disease progression in HFRS patientsCommunications biologyJune 2, 2021Liu R, Ma R, Liu Z, Hu H, Shu J, Hu P, Kang J, Zhang Y, Han M, Zhang X, et al.using CD3-APC/Cy7 (BioLegend. Cat. 300318) and PE Cyanine5 anti-human CD4 Antibody (BioLegend. Cat.317412). The specific mAb 1A8 against HTNV-NP was used to identify HTNV-infected T cells; this mAb was prepared

(13) Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemiaNPJ precision oncologyMay 26, 2021Sugita M, Wilkes DC, Bareja R, Eng KW, Nataraj S, Jimenez-Flores RA, Yan L, De Leon JP, Croyle JA, Kaner J, et al.318316), anti-CD3 BV711 (BioLegend, clone SK7, cat. 344838), anti-CD4 PE-Cy5 (BioLegend, clone OKT4, cat. 317412), anti-CD8 BV605 (BioLegend, clone SK1, cat. 344742), anti-CD19 PerCP/Cy5.5 (BioLegend, clone HIB19,

(14) MAIT cell activation is associated with disease severity markers in acute hantavirus infectionCell reports. MedicineMarch 16, 2021Maleki KT, Tauriainen J, García M, Kerkman PF, Christ W, Dias J, Wigren Byström J, Leeansyah E, Forsell MN, Ljunggren HG, et al.conjugated,BD Biosciences,"Cat#563704, clone 11A9" Mouse monoclonal anti-CD4 PE-Cy5 conjugated,BioLegend,"Cat#317412, clone OKT4, RRID: AB_571957" Mouse monoclonal anti-TCR Vα7.2 PE-Cy7 conjugated,BioLegend,"Cat#351711,

(15) Metabolic programs define dysfunctional immune responses in severe COVID-19 patientsCell reportsMarch 16, 2021Thompson EA, Cascino K, Ordonez AA, Zhou W, Vaghasia A, Hamacher-Brady A, Brady NR, Sun IH, Wang R, Rosenberg AZ, et al.Biosciences, cat. no. 563800), CD8 BV480 (BD Biosciences, cat. no. 566121), CD4 PE Cy5 (Biolegend, 317412), H3K27me3 PE (CST, cat. no. 40724) and VDAC1 AF532 (Abcam, cat. no. ab14734). Feature importance and

(16) Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19Nature immunologyJanuary 1, 2021Brunetta E, Folci M, Bottazzi B, De Santis M, Gritti G, Protti A, Mapelli SN, Bonovas S, Piovani D, Leone R, et al.anti-CD3-BUV737 (clone UCHT1, BD Biosciences, no. 564308; 1:80), anti-CD4-PECy5 (clone OKT4, BioLegend, no. 317412; 1:40), anti-CD8-BUV496 (clone RPA-T8, BD Biosciences, no. 612942; 1:40), anti-CD56-PECF594 (clone NCAM16.2,

(17) Norovirus-Specific CD8⁺ T Cell Responses in Human Blood and TissuesCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Pattekar A, Mayer LS, Lau CW, Liu C, Palko O, Bewtra M, Consortium H, Lindesmith LC, Brewer-Jensen PD, Baric RS, et al.Antibody,Clone,Source,Catalog # Anti-hu CD4 PE/CY5,OKT4,Biolegend,317411 Anti-hu CD8 BV785,RPA-T8,BD Biosciences,563823 Anti-hu CD3 BV570,UCHT1,Biolegend,300436 Anti-hu CD14

(18) A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer targetThe Journal of clinical investigationMarch 2, 2020Freeman ZT, Nirschl TR, Hovelson DH, Johnston RJ, Engelhardt JJ, Selby MJ, Kochel CM, Lan RY, Zhai J, Ghasemzadeh A, et al.(BioLegend, catalog 302606), PerCP-Cy5.5CD45RA (BioLegend, catalog 304122), PE-Cy5-CD4 (BioLegend, catalog 317412), PE-Cy7-CD8 (BioLegend, catalog 300914), APCCD28 (BioLegend, catalog 302912), and APC-Cy7-CD27 (BioLegend,

(19) Composition and dynamics of the uterine NK cell KIR repertoire in menstrual bloodMucosal immunologyMarch 1, 2017Ivarsson MA, Stiglund N, Marquardt N, Westgren M, Gidlöf S, Björkström NK.

(20) Clinical study of a survivin long peptide vaccine (SurVaxM) in patients with recurrent malignant gliomaCancer Immunology, ImmunotherapyNovember 1, 2016Robert A. Fenstermaker, Michael J. Ciesielski, Jingxin Qiu, Nuo Yang, Cheryl L. Frank, Kelvin P. Lee, Laszlo R. Mechtler, Ahmed Belal, Manmeet S. Ahluwalia, Alan D. Hutsonfluorochrome-labeled antibodies to CD8 (clone RPA-T8, FITC, Cat. 301050, BioLegend) and CD4 (clone OKT4, PE/Cy5, Cat. 317412, BioLegend) were added to remaining PBMC. The samples were acquired and analyzed by FACS as above. Analysis

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PE/Cyanine5 anti-human CD4 from BioLegend

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PE/Cyanine5 anti-human CD4 from BioLegend

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