Bioss Inc.'s MARCH4 Polyclonal Antibody, RBITC Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The MARCH4 Polyclonal Antibody, RBITC Conjugated was generated using MARCHF4 as the antigen and it reacts with Homo Sapiens, and Human.
Description
MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates