Menin (D45B1) XP ® Rabbit mAb 6891S from Cell Signaling Technology

Product Specs
ItemMenin (D45B1) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number6891S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH, M, R, Mk
TargetMEN1
HostRabbit
NCBI Gene AliasesMEAI, SCG2
ClonalityMonoclonal
NCBI Full Gene Namemenin 1
Research AreaChromatin Regulation / Nuclear Function
IsotypeIgG
CloneD45B1
Molecular Weight68

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Disparate leukemia mutations converge on nuclear phase-separated condensatesCellDecember 11, 2025Gandhar K. Datar, Elmira Khabusheva, Archish Anand, Joshua Beale, Marwa Sadek, Chun-Wei Chen, Evdokiia Potolitsyna, Nayara Alcantara-Contessoto, Guangyuan Liu, Josephine De La De La Fuente, et al.antibody (mouse),Santa Cruz B,Cat#sc-74553 anti-MENIN antibody (rabbit),Cell Signaling Technology,Cat#6891S anti-KMT2A (MLL/HRX Polyclonal Antibody) (rabbit),Active Motif,Cat#61295 anti-COILIN,Cell Signaling Technology

(2) Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timingNature Cell BiologySeptember 2, 2025Nan Xu, Hyein S. Cho, James O. S. Hackland, Silvia Benito-Kwiecinski, Nathalie Saurat, Oliver Harschnitz, Marco Vincenzo Russo, Ralph Garippa, Gabriele Ciceri, Lorenz Studeranti-H3K27me3 (Cell Signaling Technologies, #9733); rabbit anti-Menin (Cell Signaling Technologies, #6891); rabbit anti-MLL1 (Cell Signaling Technologies, #14689); rabbit anti-SUZ12 (Cell Signaling Technologies,

(3) ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1LNature GeneticsSeptember 1, 2025Weiran Feng, Erik Ladewig, Matthew Lange, Nazifa Salsabeel, Huiyong Zhao, Young Sun Lee, Anuradha Gopalan, Hanzhi Luo, Wenfei Kang, Ning Fan, et al.(1:1,000; Cell Signaling Technology, cat. no. 14689), Menin (1:1,000; Cell Signaling Technology, cat. no. 6891S), Hsp90 (1:1,000; Cell Signaling Technology, cat. no. 4877S) and Actin-HRP (horseradish peroxidase)

(4) Menin inhibitor MI-503 exhibits potent anti-cancer activity in osteosarcomaSci RepFebruary 27, 2025Shen Tian, Zhuang-Yu Hao, Deng-Hui Xu, Xuan-Zong Wang, Cheng-Cheng Shi, Yi Zhanghorseradish peroxidase antibody (n = 3) (Denville Scientific, Guangzhou, China). We purchased the Menin (#6891), PARP (#9532), Histone 3 (#4499), H3K4me1 (#5326), H3K4me2 (#9725), H3K4me3 (#9751) antibodies from

(5) High Homocysteine-Thiolactone Leads to Reduced MENIN Protein Expression and an Impaired DNA Damage Response: Implications for Neural Tube DefectsMolecular NeurobiologyOctober 1, 2024Baoling Bai, Chunlei Wan, Zonghui Xiao, Dan Li, Lingyun Liu, Kexin Zhang, Ting Zhang, Qin ZhangCST), and SET1/COMPASS Antibody Sampler Kit (#25,501, CST), including Mll1 (#14,689, CST), Menin (#6891, CST), and Wdr82 (#99,715, CST); MARS (ab180497) was purchased from Abcam. In addition, we also used

(6) Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutationsThe Journal of clinical investigationJuly 3, 2023Zhao Z, Cao K, Watanabe J, Philips CN, Zeidner JM, Ishi Y, Wang Q, Gold SR, Junkins K, Bartom ET, et al.(generated in house), anti-MLL2 (generated in house), anti-SET1A (generated in house), anti-Menin (CST, 6891), anti-MLL1C (CST, 14197), anti-RBBP5 (Bethyl Laboratories, A300-109A), anti-NCOA6 (Bethyl Laboratories,

(7) Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein InteractionJournal of medicinal chemistryJuly 11, 2019Aguilar A, Zheng K, Xu T, Xu S, Huang L, Fernandez-Salas E, Liu L, Bernard D, Harvey KP, Foster C, et al.proteins were separated by SDS-PAGE. Membranes were blotted with an anti-menin antibody (CST, catalog # 6891). Real-Time PCR: MV4;11 or MOLM-13 cells were treated for 48 h with vehicle or M-89 at 30 nM, 100

(8) Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemiaGenes & DevelopmentJanuary 1, 2019Zibo Zhao et al.Studies Hybridoma Bank. Anti-Hsp90 antibodies were purchased from Santa Cruz Biotechnology. Menin (no. 6891), LEDGF (no. 2088), MLL1N (no. 14689), MLL1C (no. 14197), ASH2L (no. 5019), PARP (no. 9542), and p21

(9) TGF-β transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 and ERK/Sp1 signaling pathwaysMolecular OncologyMarch 1, 2018Yuanyuan Zhao, Jing Ma, Yanling Fan, Zhiyong Wang, Ran Tian, Wei Ji, Fei Zhang, Ruifang Niu

(10) Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damageThe Journal of cell biologyAugust 7, 2017Burger K, Schlackow M, Potts M, Hester S, Mohammed S, Gullerova M.

(11) Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cellsOncotargetMarch 14, 2017Wang J, Zhang Y, Xu Q, Qiu J, Zheng H, Ye X, Xue Y, Yin Y, Zhang Z, Liu Y, et al.KIT-9720) for IHC with antibodies specific to menin (1:200, rabbit, Cell Signaling Technology, MA, USA, #6891), neuron-specific nuclear protein (NeuN) (1:200, Millipore, Darmstadt, Germany, ABN78), anti-single

(12) Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular DisruptionPloS oneJanuary 1, 2016Lajko M, Cardona HJ, Taylor JM, Shah RS, Farrow KN, Fawzi AA.

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Menin (D45B1) XP ® Rabbit mAb

Menin (D45B1) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (12)

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Menin (D45B1) XP ® Rabbit mAb from Cell Signaling Technology

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