INPP4b (D19B9) Rabbit mAb 8450S from Cell Signaling Technology

Product Specs
ItemINPP4b (D19B9) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8450S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetINPP4B
HostRabbit
ClonalityMonoclonal
NCBI Full Gene Nameinositol polyphosphate-4-phosphatase type II B
Research AreaCa, cAMP and Lipid Signaling
IsotypeIgG
CloneD19B9
Molecular Weight110

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Regulation of EZH2 Expression by INPP4B in Normal Prostate and Primary Prostate CancerCancers (Basel)November 15, 2023Manqi Zhang, Yasemin Ceyhan, Shenglin Mei, Taghreed Hirz, David B. Sykes, Irina U. AgoulnikSDS-PAGE and transferred to the PVDF membrane. Primary antibodies against INPP4B (Cell signaling, #8450), EZH2 (Cell signaling, #5246), AR (Millipore, #06–680), PTEN (Cell Signaling, #9188), H3K27me3 (Active

(2) Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signalingAgingDecember 1, 2020Li T, Fanning KV, Nyunoya T, Chen Y, Zou C.(Cat#:1461s), AKT1(Cat#: 2938s), AKT2 (Cat#:3063s), AKT3 (Cat#:14982s), mTOR (Cat#:2983s), INPP4b (Cat#: 8450s), PI3Kp85 (Cat#:4257s), and PDK1 (Cat#: 3062s) were from Cell Signaling (Danvers, MA, USA). pAKTThr305

(3) Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in micePLOS ONEMay 15, 2020Yasemin Ceyhan, Manqi Zhang, Jingtao Guo, Carlos G. Sandoval, Jean Vacher, Elena M. Kaftanovskaya, Alexander I. Agoulnik, Irina U. Agoulnikwere performed as previously described [27]. Rabbit polyclonal antibodies to INPP4B (1:150 dilution, #8450, Cell Signaling, Danvers, MA) and γH2A.X (1:700, #2577, Cell Signaling, Danvers, MA) were used as primary

(4) Loss of tumor suppressor inositol polyphosphate 4-phosphatase type B impairs DNA double-strand break repair by destabilization of DNA tethering protein Rad50Cell death & diseaseApril 27, 2020Sun Y, Ning X, Fan J, Hu J, Jiang Y, Hu Z, Paulo JA, Liu J, Qiu X, Xu H, et al.Promega (Fitchburg, USA), olaparib was from MCE (Monmouth Junction, USA). Antibodies against INPP4B(#8450),Akt(#9272), phospho-Akt-S473(#4060), glyceraldehyde-3-phosphate dehydrogenase (GAPDH)(#97166), phospho-p70

(5) TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversionsMolecular biology of the cellMarch 1, 2020Aki S, Yoshioka K, Takuwa N, Takuwa Y.overnight. The antibodies used are PI3K-C2α (#12402, Cell Signaling); Synj1 (K0130-3, MBL); INPP4B (#8450, Cell Signaling); total Smad2/3 (#610842, BD Bioscience); p-Smad2 (#3101, Cell Signaling); p-Smad3 (#9520,

(6) Inositol polyphosphate 4-phosphatase type II regulation of androgen receptor activityOncogeneFebruary 1, 2019Manqi Zhang, Egla Suarez, Judy L. Vasquez, Lubov Nathanson, Leif E. Peterson, Kimal Rajapakshe, Paul Basil, Nancy L. Weigel, Cristian Coarfa, Irina U. Agoulnikand 10–25 μg of protein was resolved on SDS-PAGE. Primary antibodies against INPP4B (Cell Signaling, #8450), AR (Santa Cruz Biotechnology, Dallas, TX, sc-816), pAkt S473 (Cell Signaling, #4051), pPKCζ T410 (Cell Signaling

(7) In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at EndosomesCancer discoveryJuly 1, 2015Li Chew C, Lunardi A, Gulluni F, Ruan DT, Chen M, Salmena L, Nishino M, Papa A, Ng C, Fung J, et al.(pSer473)(9018, 1:1000), anti-p-AKT2 (pSer474)(8599, 1:1000), anti-PTEN (9559, 1:1000), anti-INPP4B(8450, 1:1000) were from Cell Signaling Technology. Please note that anti-AKT2 (3063) and (5239) cross-reacted

(8) Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatmentOncotargetMarch 24, 2015Laura R. H. Ip, George Poulogiannis, Felipe Cia Viciano, Junko Sasaki, Satoshi Kofuji, Victoria J. Spanswick, Daniel Hochhauser, John A. Hartley, Takehiko Sasaki, Christina A. Gewinnerlysis buffer. Western blotting was performed with the following antibodies: Cell Signaling: INPP4B (#8450), phosphoAkt (Ser473) (#4060), Erk1/2 (#4695); Santa Cruz: PTEN (sc-6817-R), Akt 1/2 (sc-1619), BRCA1

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INPP4b (D19B9) Rabbit mAb

INPP4b (D19B9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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INPP4b (D19B9) Rabbit mAb from Cell Signaling Technology

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