The UCP-2 Polyclonal Antibody, RBITC Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to UCP2, and Uncoupling Protein 2. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The UCP-2 Polyclonal Antibody, RBITC Conjugated has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes