PGES2 Polyclonal Antibody bs-2639R from Bioss Inc.

Product Specs
ItemPGES2 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-2639R
Quantity100ul, 20uL
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
Conjugate/TagUnconjugated
ApplicationsIHC-P, WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Concentration1ug/ul
Molecular Weight42kDa
IsotypeIgG
ReactivityHuman, Mouse, Rat, Rat, Mouse, Human
Antibody TypePrimary Antibody
HostRabbit
TargetPGES2
Tissuetendon
ImmunogenKLH conjugated peptide, mouse PGES2
ClonalityPolyclonal
NCBI Gene AliasesGbf1, Mpges2, 0610038H10Rik, Pges2
NCBI Full Gene Nameprostaglandin E synthase 2

Questions and Answers

What species does this antibody react with, and has it been used in relevant studies?

The PGES2 Polyclonal Antibody is reactive with mouse, human, and rat species. It has been utilized in various studies, including immunohistochemical analyses to evaluate changes in prostaglandin E2 levels in mouse models of inflammation and other conditions, as documented in multiple publications.

Can this antibody be used for immunohistochemistry, and what are some examples of its application?

Yes, this antibody has been shown to work in immunohistochemistry. For instance, it was used to assess PGE2 levels in lung tissue sections in studies investigating the effects of various treatments on inflammation and oxidative stress in animal models, as seen in research related to asthma and subarachnoid hemorrhage.

How does the PGES2 antibody contribute to understanding inflammatory pathways in research?

The PGES2 antibody is crucial for studying the role of prostaglandin E2 in inflammatory pathways. For example, it has been employed to investigate the modulation of inflammatory cytokines and the NF-κB/COX-2 signaling pathway in various models of disease, including allergic pulmonary disease and asthma, highlighting its importance in elucidating mechanisms of inflammation.

What experimental techniques can this antibody be applied to, based on existing literature?

The PGES2 Polyclonal Antibody can be applied in several experimental techniques, including ELISA, flow cytometry, immunocytochemistry, immunofluorescence, and both frozen and paraffin-embedded tissue immunohistochemistry. Its versatility allows for comprehensive analysis of PGE2 expression in various biological contexts.

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United States

Phone: 800.501.7654 (Toll free)
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Website: www.biossusa.com

(1) Magnetic Resonance Spectroscopy Lipids Peak May Serve as a Potential Biomarker for Back Pain in Intervertebral Disc Degeneration: An Integrative Metabolomics and Proteomics Study Investigating the Role of the Lipid Droplets-Interleukin-17 Inflammatory AxisNeurospineDecember 31, 2025Xi Chen, Jiang Jiang, Yijun Dong, Shuangshuang Tu, Chuanfu Li, Wenzhi Zhang, Yongjin Li, Jun Hu(Servicebio, GB11113; 1:400 dilution), anti-TNF-α (Servicebio, GB11188; 1:200 dilution) and anti-PGE2 (Bioss, bs-2639R; 1:200 dilution). Following that, a secondary antibody was applied to the samples for an hour at room

(2) Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammationPLoS OneMay 5, 2025So-Hyeon Bok, Hae Eun Jang, Kwang-Ho Kim, Dae-Hun Park(Novus Biologicals, Centennial, CO, USA, NBP1–77894) for Th17-related change and PGE2 (Bioss, Woburn, MA, USA, bs-2639R). To quantify the result positive stained cells were counted in five non-overlapping fields of four

(3) Ginseng Berry Juice (GBJ) Regulates the Inflammation in Acute Ulcerative Mouse Models and the Major Bioactive Substances Are Ginsenosides Rb3, Rc, Rd, and ReNutrientsApril 1, 2024Soon-Young Lee, Seung-Yub Song, Sung-Ho Lee, Gye-Yeop Kim, Jin-Woo Park, Chun-Sik Bae, Dae-Hun Park, Seung-Sik ChoNF-κB (51-0500, Invitrogen, Carlsbad, CA, USA), COX-2 (ab15191, Abcam, Boston, MA, USA), and PGE2 (bs-2639R, Bioss, Woburn, MA, USA). To detect NF-κB protein or the nucleus, immunofluorescent analysis was done

(4) Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway inductionFrontiers in immunologyJanuary 1, 2024Lee SY, Le DD, Bae CS, Park JW, Lee M, Cho SS, Park DH.blocking serum from the kit to prevent nonspecific binding. The primary antibody targeting PGE2 (Bioss, bs-2639R) was applied for 1 h and then incubated with a biotinylated panspecific antibody for 30 min. Color development

(5) PLPP/CIN-mediated NF2 S10 dephosphorylation distinctly regulates kainate-induced seizure susceptibility and neuronal death through PAK1-NF-κB-COX-2-PTGES2 signaling pathwayJournal of NeuroinflammationApril 28, 2023Ji-Eun Kim, Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Min-Ju Kim, Tae-Cheon Kang(LS-C357282),1:1000 (WB)1:500 (IH) PLPP/CIN,Rabbit,Sigma (HPA001099),1:1000 (WB) PTGES2,Rabbit,Bioss (bs-2639R),1:1000 (WB)1:200 (IH) β-actin,Mouse,Sigma (#A5316),1:5000 (WB) Primary antibodies and lectin used

(6) Bifidobacterium longum BORI inhibits pain behavior and chondrocyte death, and attenuates osteoarthritis progressionPloS oneJanuary 1, 2023Oh DK, Na HS, Jhun JY, Lee JS, Um IG, Lee SY, Park MS, Cho ML, Park SH.(LTB4r; 1:100 dilution, BS-2654R, Thermo Fisher Scientific), prostaglandin E2 (PGE2; 1:250 dilution, bs-2639R, Bioss Antibodies), matrix metalloproteinase-9 (MMP9; 1:100 dilution, MA5-32705, Thermo Fisher Scientific),

(7) Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in RatsOxidative medicine and cellular longevityJanuary 1, 2022Liu Y, Liu R, Huang L, Zuo G, Dai J, Gao L, Shi H, Fang Y, Lu Q, Okada T, et al.Membranes were incubated overnight at 4°C with the following primary antibodies: anti-PGE2 (1 : 1000, BS-2639R, Bioss Antibodies Inc., Massachusetts, USA), anti-EP3 (1 : 1000, 14357-1-AP, Proteintech, Rosemont,

(8) Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGE₂ pathwaysJournal of ginseng researchJuly 1, 2021Lee SY, Kim MH, Kim SH, Ahn T, Kim SW, Kwak YS, Cho IH, Nah SY, Cho SS, Park KM, et al.with normal horse serum, were then incubated with rabbit anti-mouse PGE2 primary antibodies (1:100, bs-2639R, Bioss, MA, USA) for 1 h and were incubated again for 10 min with biotinylated secondary antibodies

(9) Saururus chinensis-controlled allergic pulmonary disease through NF-κB/COX-2 and PGE₂ pathwaysPeerJJanuary 1, 2020Song M, Lee SY, Kim M, Park S, Park J, Kwon Y, Park DH.samples prepared on slides were incubated for 1 h at 4 °C with primary antibodies (diluted 1:100, PGE2, bs-2639R, Bioss, MA, USA). All samples were incubated for 10 min to allow them to bind with secondary antibodies

(10) Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegansNature MetabolismSeptember 6, 2019Hyun Ju Lee, Alireza Noormohammadi, Seda Koyuncu, Giuseppe Calculli, Milos S. Simic, Marija Herholz, Aleksandra Trifunovic, David Vilchezand subjected to immunoblotting. Western blot analysis was performed with anti-PGES2 antibody (Bioss, bs-2639R, 1:500; RRID:AB_10860215) and α-tubulin (Sigma, T6199, 1:5,000; RRID:AB_477583). C. elegans germline

(11) Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in micePLoS biologyMarch 1, 2019Manaserh IH, Chikkamenahalli L, Ravi S, Dube PR, Park JJ, Hill JW.concentration. The primary antibodies used were as follows: IRβ (Cat. #3025S, Cell signaling); PGES2 (Cat. #bs-2639R, Bioss) [86, 87]; and GADPH (Cat.# SC-32233, Santa Cruz Biotechnology). Secondary antibodies used were

(12) Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infectionExperimental cell researchOctober 1, 2017Liu Y, Li L, Liu J, She WM, Shi JM, Li J, Wang JY, Jiang W.

(13) The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory CytokinesPain research & managementJanuary 1, 2017Chia YY, Liu CC, Feng GM, Tseng CA, Hung KC, Chen CC, Tan PH.

(14) Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendonLasers in medical scienceJanuary 1, 2015de Jesus JF, Spadacci-Morena DD, dos Anjos Rabelo ND, Pinfildi CE, Fukuda TY, Plapler H.

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PGE2 Polyclonal Antibody

PGES2 Polyclonal Antibody from Bioss Inc.

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Bioss Inc.

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PGES2 Polyclonal Antibody from Bioss Inc.

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