Choline Acetyltransferase/ChAT Antibody AF3447 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCholine Acetyltransferase/ChAT Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF3447
NCBI Gene AliasesCMS1A, CMS1A2, CHOACTASE, CMS6
ApplicationsImmunohistochemistry,Western Blot,Immunocytochemistry
ReactivityHuman,Mouse
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
IsotypeIgG
TargetCholine Acetyltransferase/ChAT
HostGoat
NCBI Full Gene Namecholine O-acetyltransferase
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human Choline Acetyltran sferase/Ch AT isoform R, Ala2-Pro630, Accession # NP_066266
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human Choline Acetyltransferase/ChAT in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Differentiation of SH-SY5Y Cells into Cortical Neuron-like Cells for Tauopathy Modeling and Seeding AssaysMolecular NeurobiologyOctober 1, 2025Alexander Devyatov, Ihor Kozlov, Viswanath DasRRID:AB_10693782(Lot: 4)",1:50 (IF)1:1000 (WB) Human Choline Acetyltransferase/ChAT Polyclonal,"R and D Systems Cat# AF3447, RRID:AB_2079603(Lot: XICO122101)",1:1000 Recombinant Anti-VGluT1 antibody [EPR22269],"Abcam Cat# ab227805,

(2) Electrophysiological characterization of sourced human iPSC-derived motor neuronsChannels (Austin)March 25, 2025Bohumila Jurkovicova-Tarabova, Robin N. Stringer, Zuzana Sevcikova Tomaskova, Norbert Weissacetyltransferase) and MAP2 (microtubule-associated protein 2) using goat polyclonal anti-CHAT (R&D Systems #AF3447) and mouse monoclonal anti-MAP2 (Sigma #M4403) antibodies, respectively. Primary antibodies were prepared

(3) AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b(-/-)Grn(-/-) miceiScienceJuly 21, 2023Feng T, Minevich G, Liu P, Qin HX, Wozniak G, Pham J, Pham K, Korgaonkar A, Kurnellas M, Defranoux NA, et al.AB_2114489 sheep anti-mouse PGRN,R&D Systems,Cat# AF2557; RRID: AB_2114504 mouse anti-CHAT,R&D Systems,Cat# AF3447 mouse anti-NeuN,Millipore,Cat# MAB377; RRID: AB_2298772 mouse anti-GFAP (GA5),Cell Signaling Technology,Cat#

(4) Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in miceEMBO reportsOctober 5, 2020Feng T, Mai S, Roscoe JM, Sheng RR, Ullah M, Zhang J, Katz II, Yu H, Xiong W, Hu F.anti‐CathD (R&D Systems, AF1029), goat anti‐CathL (R&D Systems, AF1515), mouse anti‐CHAT (R&D Systems, AF3447), mouse anti‐NeuN (Millipore, MAB377), mouse anti‐GFAP (GA5) (Cell signaling, 3670S), rabbit anti IBA‐1

(5) Notch signaling regulates motor neuron differentiation of human embryonic stem cellsStem CellsFebruary 1, 2015Ben-Shushan E, Feldman E, Reubinoff BE.

(6) Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cellNeuroreportJuly 17, 2006Zhang JQ, Yu XB, Ma BF, Yu WH, Zhang AX, Huang G, Mao FF, Zhang XM, Wang ZC, Li SN, et al.

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Choline Acetyltransferase/ChAT Antibody

Choline Acetyltransferase/ChAT Antibody

Choline Acetyltransferase/ChAT Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (6)

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Choline Acetyltransferase/ChAT Antibody from R&D Systems, a Bio-Techne Brand

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