Bioss Inc.'s AF10 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot. The AF10 Polyclonal Antibody was generated using MLLT10, and MLLT10 histone lysine methyltransferase DOT1L cofactor as the antigen and it reacts with Homo Sapiens, Human, and Rat.
Description
A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein.A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM