The HDAC8(Ser39) Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to HDAC8, and Histone Deacetylase 8. This antibody recognizes Homo Sapiens, and Human antigen. The HDAC8(Ser39) Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter