HMGCR (Ser872) Polyclonal Antibody bs-4063R from Bioss Inc.

Product Specs
ItemHMGCR (Ser872) Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-4063R
Quantity100ul, 20uL
ApplicationsWB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), WB
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
Conjugate/TagUnconjugated
Concentration1ug/ul
Molecular Weight95-97kDa
IsotypeIgG
ReactivityHuman, Mouse, Rat, Rabbit, Human
Antibody TypePrimary Antibody
TargetHMGCR Ser872
HostRabbit
ModificationsSer872
ImmunogenKLH conjugated phosphopeptide, human HMGCR around Ser872
ClonalityPolyclonal
NCBI Gene AliasesLDLCQ3, MYPLG
NCBI Full Gene Name3-hydroxy-3-methylglutaryl-CoA reductase

Questions and Answers

Can this antibody be used to study the phosphorylation status of HMGCR in muscle tissues?

Yes, the HMGCR (Ser872) Polyclonal Antibody has been utilized in studies to assess the phosphorylation of HMGCR, particularly in the context of muscle tissues. For instance, it was employed to analyze the phosphorylation levels of HMGCR in skeletal muscle following exercise, as detailed in the research by Wang et al. (2021) .

Is this antibody effective for use in Western blotting applications?

The HMGCR (Ser872) Polyclonal Antibody has been shown to work effectively in Western blotting applications, as indicated by its use in various studies, including those that investigate the mevalonate pathway and its role in signaling pathways related to muscle function .

What species can this antibody react with, and is it suitable for cross-species studies?

This antibody is reactive with multiple species, including humans, mice, and rats. This broad reactivity makes it suitable for cross-species studies, allowing researchers to investigate the role of HMGCR in different biological contexts across these species.

Are there any specific experimental conditions or dilutions recommended for using this antibody in immunofluorescence?

The HMGCR (Ser872) Polyclonal Antibody has been cited in studies where it was used at a dilution of 1:500 for immunofluorescence staining, which suggests this dilution may be effective for similar applications .

Bioss Inc.

300 Tradecenter Drive

Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
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Company Profile

Website: www.biossusa.com

(1) The vitamin D receptor is essential for the replication of pseudorabies virusmBioDecember 11, 2024Lei Zeng, Shu-Yi Wang, Meng-Hua Du, Bei-Bei Chu, Sheng-Li Mingfrom Abcam. The anti-HMGCR (MABS1233) antibody was purchased from Sigma-Aldrich. The anti-p-HMGCR (bs-4063R) antibody was purchased from Bioss. Mouse monoclonal antibody against PRV VP16 was a gift from Jing-Fei

(2) Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replicationVirologica SinicaJune 1, 2024Xiu-Qing Li, Meng-Pan Cai, Ming-Yang Wang, Bo-Wen Shi, Guo-Yu Yang, Jiang Wang, Bei-Bei Chu, Sheng-Li Minganti-puromycin (MABE343) and anti-HMGCR (MABS1233) was purchased from Sigma-Aldrich (MO, USA); anti-p-HMGCR (bs-4063R) was purchased from Bioss (MA, USA); horseradish peroxidase (HRP)-conjugated donkey anti-mouse IgG (715-035-150)

(3) Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in ratsPhysiological reportsMarch 1, 2024Uda M, Yoshihara T, Ichinoseki-Sekine N, Baba T.(rabbit polyclonal),Bioss,bs‐0472,AB_10856433,1:5000 Bioss,Phospho‐HMGCR(Ser872) (rabbit polyclonal),bs‐4063R,AB_10856788,1:5000 PDHA1 (phospho‐S293) (rabbit monoclonal),Abcam,ab177461,AB_2756339,1:5000 Phospho‐ACLY(Ser455)

(4) EGCG Restricts PRRSV Proliferation by Disturbing Lipid MetabolismMicrobiology SpectrumApril 27, 2022Peng-Wei Yu et al.from Abcam (MA, USA); anti-HMGCR (MABS1233) was ordered from Sigma-Aldrich; anti-phosphorylated HMGCR (bs-4063R) was ordered from Bioss (MA, USA); anti-PRRSV nucleocapsid (N) SDOW17 was ordered from Rural Technologies

(5) Reduced membrane cholesterol content in skeletal muscle is not essential for greater insulin-stimulated glucose uptake after acute exercise by ratsApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolismeJune 1, 2021Wang H, Arias EB, Cartee GD.Anti-HMG-CoA Reductase (HMGCR, #BS-5068R) and anti-phospho HMG-CoA Reductase Ser872 (pHMGCRSer872, #BS-4063R) were from Bioss Antibodies (Woburn,MA). Anti-ATP Binding Cassette Subfamily A Member 1 (ABCA1, #NB400-105SS)

(6) Hempseed Peptides Exert Hypocholesterolemic Effects with a Statin-Like MechanismJournal of agricultural and food chemistryOctober 11, 2017Zanoni C, Aiello G, Arnoldi A, Lammi C.

(7) Hypocholesterolaemic Activity of Lupin Peptides: Investigation on the Crosstalk between Human Enterocytes and Hepatocytes Using a Co-Culture System Including Caco-2 and HepG2 CellsNutrientsJuly 22, 2016Lammi C, Zanoni C, Ferruzza S, Ranaldi G, Sambuy Y, Arnoldi A.

(8) HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell deathThe Journal of general virologyJune 1, 2014Yang X, Ouyang H, Chen F, Pang D, Dong M, Yang S, Liu X, Peng Z, Wang F, Zhang X, et al.

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HMGCR (Ser872) Polyclonal Antibody

HMGCR (Ser872) Polyclonal Antibody from Bioss Inc.

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Questions and Answers

Bioss Inc.

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HMGCR (Ser872) Polyclonal Antibody from Bioss Inc.

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