Bioss Inc.'s Caspase-7 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot. The Caspase-7 Polyclonal Antibody was generated using CASP7 as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-:-Gly-217' bond. Overexpression promotes programmed cell death