Bax Polyclonal Antibody bs-0127R from Bioss Inc.

Product Specs
ItemBax Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-0127R
NCBI Gene AliasesBCL2L4
Molecular Weight21kDa
ImmunogenKLH conjugated peptide, human Bax
ReactivityRabbit, Pig, Rat, Human, Zebrafish, Human, Mouse, Rat, Rabbit, Chicken, Bovine, Mouse
ApplicationsWB, WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), IP, IP, WB, IHC-P, WB, IHC, WB, IF(IHC-P), IHC, WB, IF, IF(ICC), IHC-P, IF
ClonalityPolyclonal
IsotypeIgG
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
Antibody TypePrimary Antibody
Quantity100ul, 20uL
Conjugate/TagUnconjugated
HostRabbit
TargetBax
Concentration1ug/ul
NCBI Full Gene NameBCL2 associated X, apoptosis regulator
TissueHeart, Testis, Brain, testis, brain, Liver, liver

Questions and Answers

Can this Bax antibody be used in immunohistochemistry for studying apoptosis in corneal epithelial cells?

Yes, the Bax Polyclonal Antibody has been utilized in immunohistochemistry to assess the presence of Bax in corneal epithelial cells, particularly in studies investigating the effects of blue light on apoptosis and wound healing in these cells ().

Is the Bax antibody effective for detecting apoptosis in bovine mammary epithelial cells?

The Bax Polyclonal Antibody has been shown to be effective in detecting apoptosis in bovine mammary epithelial cells, particularly in studies examining the role of Sirtuin 5 in regulating apoptosis and autophagy under ammonia-induced stress conditions ().

How has the Bax antibody been applied in research related to pancreatic cancer?

The Bax Polyclonal Antibody has been employed in studies investigating the apoptotic pathways in pancreatic cancer cells, where it was used to analyze protein expression levels in response to various treatments, including photodynamic therapy ().

What is the significance of using the Bax antibody in studies of drug resistance in gastric cancer?

The Bax Polyclonal Antibody has been used in research focused on the role of tetraspanin-8 in drug resistance in gastric cancer, where it helped to elucidate the mechanisms of apoptosis in multidrug-resistant cell lines ().

Bioss Inc.

300 Tradecenter Drive

Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
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Company Profile

Website: www.biossusa.com

(1) Resveratrol inhibits renal ischemia and reperfusion injury in diabetes via reducing oxidative stress, inflammation, and apoptosisRen FailApril 10, 2026Daojing Gong, Xiaobo Chen, Ziqiang Dong, Huan Chen, Ziqiang LiuB-cell lymphoma-2 (Bcl-2; cat. no. GB154830; 1:1,000; Servicebio), Bcl-2-associated X protein (Bax; cat. no. BS-0127R; 1:1,000; BIOSS), and cleaved caspase-3 (cat. no. 9661 T; 1:1,000; Cell Signaling Technology), respectively.

(2) Remote Ischemic Preconditioning Exerts Neuroprotective Effects Via the PGC-1α/FNDC5/BDNF Pathway in Focal Brain Ischemia of RatsTransl Stroke ResMarch 9, 2026Teruki Matsuoka, Ryoma Matsuzaki, Kazuki Nakanishi, Shogo Kakimoto, Yuki Kato, Shotaro Otsuka, Kiyoshi Kikuchi, Harutoshi SakakimaCell Signaling), rabbit anti-Bcl-2 antibody (1:1000; bs-4563R; Bioss Inc., Woburn, USA), rabbit anti-Bax antibody (bs-0127R; Bioss Inc., Woburn, USA), rabbit anti-caspase-3 (1:1000; 19677-1-AP; Proteintech), and anti-mouse alpha-tubulin

(3) Taurine Alleviates Inflammation, Oxidative Stress, Apoptosis, and Uterus Microbiota Dysregulation of Endometritis by Inhibiting PI3K-AKT/MAPK/NF-κB Pathways in MiceAnimals (Basel)December 16, 2025Jianxu Xiao, Chongliang Bi, Ming Yang, Chen Chen, Juanjuan Zhao, Xiaoqing Huang, Jingyuan Zhang, Buwei Yin, Ke Li, Yuzhong MaUSA)",#8690,1:1000 phospho-p38,CST,#4a511,1:1000 ERK,CST,#4695T,1:1000 phospho-ERK,CST,#4370T,1:2000 JNK,CST,#9252T,1:1000 phospho-JNK,CST,#4668T,1:1000 HO-1,Bioss,bs-2075R,1:1000 NQO1,Bioss,bs-2184R,1:2000 Keap1,Bioss,bs-4900R,1:2000 Nrf2,Bioss,bs-1074R,1:500 Bcl-2,Bioss,bs-4563R,1:1000 Bax,Bioss,bs-0127R,1:1000 Caspase-3,Bioss,bs-0081R,1:1000 Cleaved-Caspase3,"HUABIO (HUABIO LLC, Fremont, CA, USA)",ET1602-47,1:2000 Cytochrome C

(4) Variations in conventional and non-conventional semen characteristics of selected rabbit breedsAnimal BiotechnologyDecember 12, 2025Eva Tvrdá, Filip Benko, Michal Ďuračka, Anton Kováčik, Jakub Vozaf, Andrea Svoradová, Jaromír Vašíček, Andrej Baláži, Peter Supuka, Simona Kunová, et al.the membranes were incubated with one of the following primary antibodies:Bax Polyclonal Antibody (# BS-0127R; Bioss Antibodies Inc.); 1:1 000 in 5% milk in TBS/0.1% Tween-20.Bcl-2 Polyclonal Antibody (# BS-0032R;

(5) IDHP Mitigates LPS-Induced Cardiomyocyte Injury via the GAS6/Axl-AMPK Axis: A Multi-Target Strategy Counteracting Inflammation, Oxidative Stress, and ApoptosisPharmaceuticals (Basel, Switzerland)August 12, 2025Chen J, Wang Y, Li X, Guo X, Tian J, Zheng X, Yang Y, Cao Y.Numbers GAS6,"Servicebio, Wuhan, China",GB11636 Axl,"Bioss, Woburn, MA, USA",bs-5180R Bax,"Bioss, Woburn, MA, USA",bs-0127R Nrf2,"Boster Biological Technology, Pleasanton, CA, USA",A00078-1 AMPK,"Abcam, Cambridge, UK",ab110036 p-AMPK,"Bimake,

(6) Esculetin inhibits the PI3K/Akt/mTOR pathway and enhances anti-colorectal cancer activity via binding to ENO1Front PharmacolJuly 16, 2025Jianing Ma, Miaomiao Zhang, Shulipan Mulati, Xinhua Nabi, Weiyi Zhangantibodies The Esc (HPLC≥98%, B20991) was purchased from Yuanye (Shanghai, China). Antibodies against Bax (bs-0127R), Bcl-2 (bs-0032R), and Mcl-1 (bs-23315R) were procured from Bioss (Beijing, China). Antibodies against

(7) Cytotoxic and proapoptotic effects of alizarin in mice with Ehrlich solid tumor: novel insights into ERα-mediated MDM2/p-Rb/E2F1 signaling pathwayNaunyn-Schmiedeberg's Archives of PharmacologyJune 28, 2025Aya H. Eid, Ahmed A. Al-Karmalawy, Reda F. A. Abdelhameed, Yasser M. Mostafa, Gouda K. Helal, Eman T. Mehanna, Reem M. Hazemmanufacturer's instructions (Dako, Glostrup, Denmark). Primary polyclonal antibodies for p53 (bs- 0033R), Bax (bs- 0127R), and ERα (bsm- 53007 M) (Bioss Inc., Woburn, MA, USA) were diluted in PBS (normal phosphate buffered

(8) Melatonin Alleviates MBP-Induced Oxidative Stress and Apoptosis in TM3 Cells via the SIRT1/PGC-1α Signaling PathwayInt J Mol SciJune 19, 2025Jingjing Liu, Qingcan Guan, Shuang Li, Qi Qi, Xiaoyan PanBIOSS, Beijing, China; #bs-4563R), cleaved-caspase3 (1:1000, #A27145, ABclonal), Bax (1:1000, BIOSS, #bs-0127R), and β-actin (1:100,000, ABclonal, #AC026). After washing, the membrane was incubated with a goat anti-rabbit

(9) Sirtuin 5 inhibits mitochondrial metabolism in liver cancer cells and promotes apoptosis by mediating the desuccinylation of CSFront ImmunolJune 10, 2025Huimin Cao, Dongsheng Wei, Han Li, Mei Zhao, Yixin Ma, Liang Kong, Guoyuan Sui, Lianqun Jiaglyceraldehyde 3 -phosphate dehydrogenase (GAPDH) (Bioss; bs-10900R; 1/10,000); Rabbit Anti-Bax antibody (Bioss; bs-0127R; 1/1000); Rabbit Anti-Caspase-3 antibody (Bioss; bs-0081R; 1 1/1000); Bcl2 Monoclonal antibody (proteintech;

(10) NOXA exacerbates endoplasmic-reticulum-stress-induced intervertebral disc degeneration by activating apoptosis and ECM degradationCell Death DiscovMay 28, 2025Zhiming Liu, Hui Lu, Xianjuan Zhang, Shuai Tang, Antao Lin, Shuo Han, Xuexiao MaNOXA (ab222852, 1:1000, Abcam, Cambridge, UK), PERK (bs-2469R, 1:1000, Bioss, Beijing, China), BAX (bs-0127R, 1:1000, Bioss, Beijing, China), BCL-2 (bs-0032R, 1:2000, Bioss, Beijing, China), MCL-1 (16225-1-AP,

(11) Mechanism of total saponins of Ranunculus ternatus Thunb. in treatment of breast cancer based on liquid chromatography–mass spectrometry and network analysisFrontiers in PharmacologyApril 25, 2025Yuanxin Zhang, Shuo Nan, Wei Zhao, Haisheng Xie, Jinxin Miao, Mingsan Miao(Wuhan Procell Life Science & Technology; PM150110A); rabbit anti-Bax primary antibody (Beijing Bioss; bs-0127R); rabbit anti-Bcl-2 primary antibody (Beijing Bioss; bs-4563R); rabbit GAPDH (GAPDH; Wuhan Sanying Biotechnology;

(12) MiR-27a-3p protects against NaAsO2-induced neuronal apoptosis in HT22 cellsSci RepApril 23, 2025Qiyao Zhang, Siqi Zhao, Teng Ma, Yujie Wang, Shiqing Xu, Suhua Wang, Xiaohui Wang, Li Wanganti-DRP1 (1:1000, CAT# 40853, SAB), anti-p-DRP1 (Ser616) (1:1000, CAT# 53847, SAB), anti-Bax (1:1000, CAT#BS0127R, BIOSS, Beijing, China), anti-Bcl-2 (1:1000, CAT# BSM33411M, BIOSS), or anti-Cleaved-caspase 3 (1:800,

(13) CircRNA profiling reveals the regulatory role of circPAN3 in Hezuo boars Sertoli cell growthBMC GenomicsDecember 30, 2024Haixia Shi, Zunqiang Yan, Hong Du, Bo Zhang, Shuangbao Gun5% skim milk for 1 h and then incubated with primary antibody PCNA (bs-2007R, Bioss; 1:1000), Bax (bs-0127R, Bioss; 1:1000), Bcl-2 (bs-4563R, Bioss; 1:1000), and Caspase-3 (bs-0081R, Bioss; 1:1000) at 4 °C overnight.

(14) TGF-β1 maintains the developmental potential of embryonic submandibular gland epithelia separated with mesenchymeHeliyonJuly 15, 2024Li H, Wang G, Zhao G, Liu H, Liu L, Cao Y, Li C.Dallas, USA), SOX2 (WL03767, Wanlelbio, Shenyang, China), BCL-2 (bs-4563R, Bioss, Beijing, China), BAX (bs-0127R, Bioss, Beijing, China), cleaved Caspase-3 (9661, Cell Signaling Technology, Danvers, USA), Caspase-3

(15) Transcription factor FOXF2 promotes the development and progression of pancreatic cancer by targeting MSI2Oncology ReportsJune 4, 2024Bang-Hua Zhong, Yu-Teng Ma, Jian Sun, Jing-Tong Tang, Ming Dongbsm-52197R; BIOSS), anti-Cleaved caspase-3 (1:500; cat. no. bs-20364R; BIOSS), anti-Bax (1:500; cat. no. bs-0127R; BIOSS), anti-Bad (1:500; cat. no. bs-0892R; BIOSS), anti-Bcl-xl (1:1,000; cat. no. bsm-52024R; BIOSS),

(16) Sirtuin 5 alleviates apoptosis and autophagy stimulated by ammonium chloride in bovine mammary epithelial cellsExperimental and Therapeutic MedicineMay 22, 2024Junhui He, Luping Feng, Hanlin Yang, Shikai Gao, Jinru Dong, Guangyang Lu, Luya Liu, Xinyi Zhang, Kai Zhong, Shuang Guo, et al.Mouse anti-Bcl-2 antibody (cat. no. bsm-33047M; 1:500 dilution), rabbit anti-Bax antibody (cat. no. bs-0127R; 1:500), rabbit anti-β-actin antibody (cat. no. bs-33036M; 1:1,000), rabbit anti-Caspase-3 antibody

(17) B-Myb deficiency boosts bortezomib-induced immunogenic cell death in colorectal cancerScientific ReportsApril 2, 2024Yuan-Jian Hui, Ting-Ting Yu, Liu-Gen Li, Xing-Chun Peng, Mao-Jun Di, Hui Liu, Wen-Long Gu, Tong-Fei Li, Kai-Liang Zhao, Wei-Xing WangCydlinD1 (26939-1-AP, Proteintech, Wuhan, China), CDC25A (55031-1-AP, Proteintech, Wuhan, China), Bax (bs-0127R, Bioss, Beijing, China), Caspase-3 (50599-2-Ig, Proteintech, Wuhan, China), PCNA (bs-2006R, Bioss, Beijing,

(18) Efficient Assessment of Tumor Vascular Shutdown by Photodynamic Therapy on Orthotopic Pancreatic Cancer Using High-Speed Wide-Field Waterproof Galvanometer Scanner Photoacoustic MicroscopyInt J Mol SciMarch 19, 2024Jaeyul Lee, Sangyeob Han, Til Bahadur Thapa Magar, Pallavi Gurung, Junsoo Lee, Daewoon Seong, Sungjo Park, Yong-Wan Kim, Mansik Jeon, Jeehyun Kimblotted with different primary antibodies diluted in blocking solution at 4 °C: anti-rabbit anti-bax (bs-0127R, Bioss, Woburn, MA, USA), anti-mouse anti-Bcl-2 (bs-52022M, Bioss, Woburn, MA, USA), anti-rabbit β-Actin

(19) Qingzhuan dark tea Theabrownin alleviates hippocampal injury in HFD-induced obese mice through the MARK4/NLRP3 pathwayHeliyonMarch 15, 2024Yining Lei, Yong Chen, Shuo Zhang, Wei Wang, Min Zheng, Ruyi Zhangrabbit anti-GFAP (bs-0199R, Bioss, 1:200), rabbit anti-Iba1 (A19776, ABconal, 1:200), rabbit anti-BAX (bs-0127R, Bioss, 1:200). The secondary antibody used is donkey anti-rabbit Alexa Fluor568 (A10042, Invitrogen,

(20) Dermal FOXO3 activity in response to Wnt/β-catenin signaling is required for feather follicle development of goose embryos (Anser cygnoides)Poultry ScienceMarch 1, 2024Sihui Wang, Yudong Wang, Xiangman Hu, Yuxuan Zhou, Zhiyi Yang, Jiahui Hou, Fengshuo Liu, Qiuyuan Liu, Ichraf Mabrouk, Jin Yu, et al.anti-phospho-FOXO3A (Ser-253) (Cat# AF3020, Affinity, Changzhou, China), anti-Bax protein antibodies (Cat# bs-0127R, Bioss, Beijing, China), anti-Bcl2 protein antibodies(Cat# bs-0032R, Bioss, Beijing, China), anti-PCNA

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