VCAM-1 Polyclonal Antibody bs-0396R from Bioss Inc.

Product Specs
ItemVCAM-1 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-0396R
Molecular Weight81kDa
ImmunogenKLH conjugated synthetic peptide derived from mouse VCAM-1
Quantity100ul, 20uL
Conjugate/TagUnconjugated
ClonalityPolyclonal
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ReactivityHuman, Mouse, Mouse, Rat, Mouse
Antibody TypePrimary Antibody
IsotypeIgG
ApplicationsWB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), WB
HostRabbit
TargetVCAM-1
Concentration1ug/ul
NCBI Gene AliasesCD106, Vcam-1
NCBI Full Gene Namevascular cell adhesion molecule 1

Questions and Answers

Can this VCAM-1 antibody be used to study interactions with T lymphocytes in endothelial cells?

Yes, the VCAM-1 Polyclonal Antibody has been utilized in studies examining the functional interactions between luteal endothelial cells and T lymphocytes. Specifically, it has been shown to play a role in mediating adhesion and signal transduction, which is critical for understanding immune responses and leukocyte emigration to sites of inflammation ().

Is this antibody effective for detecting VCAM-1 in Western blotting applications?

The VCAM-1 Polyclonal Antibody has been successfully employed in Western blotting, as evidenced by its use in various studies to analyze protein expression levels, including in the context of myocardial ischemia/reperfusion injury where VCAM-1 was a key focus ().

What species can this antibody react with, and how does that impact its use in experiments?

This antibody is reactive with mouse, human, and rat species. This broad reactivity allows for its application in comparative studies across different model organisms, which is beneficial for translational research and understanding the role of VCAM-1 in various biological contexts.

Are there any specific pathways or conditions where VCAM-1 expression is particularly relevant?

Yes, VCAM-1 expression has been implicated in the TLR4/MAPK signaling pathway, particularly in the context of inflammation and deep vein thrombosis. Studies have shown that S100A8 can enhance VCAM-1 expression, indicating its role in inflammatory responses and potential as a biomarker for conditions like acute deep vein thrombosis ().

Bioss Inc.

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Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
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Company Profile

Website: www.biossusa.com

(1) Preliminary clinical analysis and pathway study of S100A8 as a biomarker for the diagnosis of acute deep vein thrombosisScientific ReportsJune 10, 2024Wenjie Zeng, Yangyang Gao, Qitao Wang, Junyu Chi, Ziyan Zhu, Qingfei Diao, Xin Li, Zhen Wang, Ming Qu, Yongquan ShiUnited States), anti-p38MAPK (bs-0637R; Bioss, China), anti-ICAM-1 (bs-0608R; Bioss), and anti-VCAM-1 (bs-0396R; Bioss) at 4 °C. Subsequently, the indicated goat anti-rabbit secondary antibody (C31460100C; Thermo

(2) CXCR1 and its downstream NF-ÎºB inflammation signaling pathway as a key target of Guanxinning injection for myocardial ischemia/reperfusion injuryFrontiers in ImmunologyOctober 17, 2022Guangxu Xiao, Jiaxu Liu, Huanyi Wang, Shuang He, Jianwei Liu, Guanwei Fan, Ming Lyu, Yan ZhuLife Science (Pittsburgh, United States). Anti-CXCR1 antibody (bs-1009R) and anti-VCAM-1 antibody (bs-0396R) were purchased from Bioss (Beijing, China). Anti-COX2 antibody (12282S) was purchased from Cell Signaling Technology

(3) Eicosapentaenoic acid in the form of phospholipids exerts superior anti-atherosclerosis effects to its triglyceride form in ApoE(-/-) miceFood & functionJuly 17, 2019Zhang LY, Ding L, Shi HH, Xu J, Xue CH, Zhang TT, Wang YM.

(4) Interferon-γ facilitated adjuvant-induced arthritis at early stageScandinavian journal of immunologyMay 1, 2019Ma H, Xu M, Song Y, Zhang T, Yin H, Yin S.

(5) Isolation of luteal endothelial cells and functional interactions with T lymphocytesReproductionMay 1, 2017S S Walusimbi, L M Wetzel, D H Townson, J L Patepolyvinylidene difluoride membranes (Hybond-P; Amersham Pharmacia Biotech) and polyclonal rabbit anti mouse VCAM1 antibody (bs-0396R; Bioss). Isolation of cells Corpora lutea were collected transvaginally from cyclic Holstein cows following

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VCAM-1 Polyclonal Antibody

VCAM-1 Polyclonal Antibody from Bioss Inc.

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VCAM-1 Polyclonal Antibody from Bioss Inc.

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