The Syntaxin Antibody from Bioss Inc. is a Mouse Monoclonal antibody to STX1A, and Syntaxin 1A. This antibody recognizes Homo Sapiens, Human, Rat, Hamster, and Porcine antigen. The Syntaxin Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010)