The MAP1LC3A Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to MAP1LC3A. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The MAP1LC3A Polyclonal Antibody has been shown to work in the following applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Microtubule-associated MAPILC3A constitutes nearly half of the mass of all the microtubule associated proteins that copurify with brain microtubules. MAP1LC3A is one of three human orthologs of the rat Map1LC3, (named MAP1LC3A, MAP1LC3B, and MAP1LC3C). The three isoforms of human MAP1LC3 exhibit distinct expression patterns in different human tissues and also differ in their post-translation modifications. MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue; MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form