IL-23R Polyclonal Antibody bs-1460R from Bioss Inc.

Description

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis

Product Specs
ItemIL-23R Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-1460R
Molecular Weight67kDa
ImmunogenKLH conjugated peptide, human IL-23R
IsotypeIgG
ReactivityHuman, Mouse, Rat, Mouse, Dog, Mouse
Antibody TypePrimary Antibody
Conjugate/TagUnconjugated
ApplicationsWB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), WB, Others
ClonalityPolyclonal
Quantity100ul, 20uL
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
TargetIL-23R
HostRabbit
Concentration1ug/ul
NCBI Full Gene Nameinterleukin 23 receptor
TissueBrain
NCBI Gene AliasesPSORS7

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Questions and Answers

What species can I use this IL-23R antibody on for my experiments?

This IL-23R Polyclonal Antibody has been shown to work with canine, mouse, and human tissues, making it versatile for studies involving these species.

Can this antibody be used for immunohistochemistry, and if so, what tissues have been studied?

Yes, the IL-23R Polyclonal Antibody is suitable for immunohistochemistry applications. It has been utilized in studies involving brain tissue, which may provide insights into its role in immune responses and potential involvement in autoimmune diseases.

How does this antibody interact with IL-23, and what implications does this have for my research on immune responses?

The IL-23R Polyclonal Antibody binds to IL-23 and mediates the stimulation of T-cells, NK cells, and possibly certain macrophage/myeloid cells through the Jak-Stat signaling cascade. This interaction is crucial for understanding innate and adaptive immunity, particularly in the context of acute responses to infection and autoimmune inflammatory diseases.

Is there any published research that supports the use of this antibody in specific applications?

Yes, the IL-23R Polyclonal Antibody has been cited in two scientific articles, indicating its relevance and application in research related to interleukin-23 receptor functions and associated immune mechanisms.