The Anti-CD47 [ZF1] Antibody from MyBioSource.com Monoclonal antibody to CD47. This antibody recognizes Homo Sapiens, and Human antigen. The Anti-CD47 [ZF1] Antibody has been shown to work in the following applications: EIA, Immunoassay, Block/Neutralize/Inhibit, ELISA, and Flow Cytometry.
Description
The original antibody was isolated after screening of three lambda3-H3, lambda3-H5 and lambda1-H3 phage display single-chain variable fragments (scFvs) libraries by panning against recombinant protein antigen CD47-His. The variable domain genes of the antibody were cloned into a pair of eukaryotic cell expression vectors and co-transfected into FreeStyle HEK293T cells for expression and obtaining the IgG antibody.
Decribes the generation of a human fully blocking anti-CD47 antibody.
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques