The Toll-Like Receptor 7 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to TLR7. This antibody recognizes Homo Sapiens, and Human antigen. The Toll-Like Receptor 7 Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response