The COL17A1 Rabbit Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to COL17A1. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The COL17A1 Rabbit Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiProtein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]