MyBioSource.com's Angiopoietin 1 Rabbit mAb is a Rabbit monoclonal antibody. The Angiopoietin 1 Rabbit mAb Antibody was generated using Angiopoietin 1, and ANGPT1 as the antigen. It reacts with Homo Sapiens, Human, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context