The Phospho-Histone H3 (Thr3) Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to H3-3A, H3-3B, H3.3 histone A, and H3.3 histone B. This antibody recognizes Homo Sapiens, and Human antigen. The Phospho-Histone H3 (Thr3) Rabbit mAb Antibody has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling