Rabbit Anti-PKA alpha/beta CAT Antibody from MyBioSource.com

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Rabbit Anti-PKA alpha/beta CAT Antibody

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MyBioSource.com's Rabbit Anti-PKA alpha/beta CAT Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot. The Rabbit Anti-PKA alpha/beta CAT Antibody was generated using PRKACA as the antigen and it reacts with Homo Sapiens, Human, and Mouse.

Description

Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts