MyBioSource.com's Histone H4 (tri methyl K20) Rabbit mAb is a Rabbit monoclonal antibody. The Histone H4 (tri methyl K20) Rabbit mAb Antibody was generated using H4 clustered histone 15, H4 histone 16, and H4C15 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling