The Rabbit Anti-alpha Adaptin/AP2A1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AP2A1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Anti-alpha Adaptin/AP2A1 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
AP-2 complex subunit alpha-1 is a protein that in humans is encoded by the AP2A1 gene. This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined