The Histone H3 (acetyl K14) Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to H3 clustered histone 1, and H3C1. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The Histone H3 (acetyl K14) Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers