MyBioSource.com's Histone H2A (hydroxyl Y39) Rabbit mAb is a Rabbit monoclonal antibody. The Histone H2A (hydroxyl Y39) Rabbit mAb Antibody was generated using H2A clustered histone 4, H2A clustered histone 8, H2AC4, and H2AC8 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
H2A.1 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability