The Anti-NDRG3 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The Anti-NDRG3 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
N-Myc downstream-regulated gene 3 (NDRG3) is one of the important members of the NDRG family which crucially take part in cell proliferation, differentiation, and other biological processes. NDRG3 plays important role in human cancer, and its expression may be considered as an oncogenic biomarker and a novel predictor for HCC prognosis. For example, NDRG3 facilitates colorectal cancer (CRC) migration and invasion by activating Src phosphorylation, suggesting the role of NDRG3 as a candidate oncogene; NDRG3 downregulation might be involved in the tumorigenesis and development of invasive breast cancer (BC) in an advanced phase of the disease. NDRG3 belongs to the N-Myc down-regulated gene (NDRG) family that contains 4 paralogs: NDRG1, -2, -3, and -4