The PI 3 kinase p110 alpha Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to PIK3CA. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The PI 3 kinase p110 alpha Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors