The Rabbit Anti-CaMKIIalpha/beta/delta Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Camk2a. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Anti-CaMKIIalpha/beta/delta Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
calcium/calmodulin dependent protein kinase II alpha (CAMK2A) Homo sapiens The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]