The ZFAND5 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ZFAND5. This antibody recognizes Mouse antigen. The ZFAND5 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF, IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. is potent inhibitory factor for osteoclast differentiation