MyBioSource.com's Anti-Perforin APC monoclonal antibody. The Anti-Perforin APC Antibody was generated using Perforin 1, and PRF1 as the antigen. It reacts with Homo Sapiens, Human, and Bovine. This antibody has been shown to work in applications such as: Cell Sorting, Isolation, Flow Cytometry, and Immunofluorescence.
Description
Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders