The Thyroid Transcription Factor 1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to NKX2-1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Thyroid Transcription Factor 1 Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer