The Histone H2A.X Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to H2A.X variant histone, and H2AX. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Histone H2A.X Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability