MyBioSource.com's Rabbit Anti-GluR1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Rabbit Anti-GluR1 Antibody was generated using GRIA1 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptor is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. The level of phosphorylated GluR1 at two major sites implicated in GluR regulation for further research of the mechanisms underlying synaptic plasticity