HMGB2 Rabbit mAb from MyBioSource.com

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HMGB2 Rabbit mAb

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MyBioSource.com's HMGB2 Rabbit mAb is a Rabbit monoclonal antibody. The HMGB2 Rabbit mAb Antibody was generated using Hmgb2 as the antigen. It reacts with Homo Sapiens, Human, Mouse, Rat, and Hamster. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, Immunoprecipitation, and Western Blot.

Description

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V (D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS)