MyBioSource.com's TBK1 Rabbit mAb is a Rabbit monoclonal antibody. The TBK1 Rabbit mAb Antibody was generated using TBK1 as the antigen. It reacts with Homo Sapiens, Human, Rat, and Hamster. This antibody has been shown to work in applications such as: Western Blot.
Description
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex