The Rabbit Anti-Transmembrane Protein 173 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to stimulator of interferon response cGAMP interactor 1, and STING1. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The Rabbit Anti-Transmembrane Protein 173 Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants