The DRAP1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to DRAP1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The DRAP1 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Transcriptional repression is general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]