The PAK1IP1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PAK1IP1. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The PAK1IP1 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Negatively regulates the PAK1 kinase. PAK1 is member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly