The Rabbit Anti-Cytochrome C Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to CYCS. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Anti-Cytochrome C Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Cytochrome c is 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy