CHRND Polyclonal Antibody from MyBioSource.com

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CHRND Polyclonal Antibody

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The CHRND Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CHRND. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The CHRND Polyclonal Antibody has been shown to work in the following applications: Western Blot.

Description

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene