MyBioSource.com's Ubiquitin Conjugating Enzyme E2 N Rabbit mAb is a Rabbit monoclonal antibody. The Ubiquitin Conjugating Enzyme E2 N Rabbit mAb Antibody was generated using UBE2N as the antigen. It reacts with Homo Sapiens, Human, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation