The Rabbit Anti-PMEL Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to PMEL. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit Anti-PMEL Antibody has been shown to work in the following applications: Flow Cytometry.
Description
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes; which are the melanin-producing organelles in melanocytes; and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants