MyBioSource.com's NFATC2IP Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The NFATC2IP Polyclonal Antibody was generated using NFATC2IP as the antigen and it reacts with Homo Sapiens, and Human.
Description
In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity